Publications

2024

Untangling plastic responses to combined thermal and dietary stress in insects.

Chakraborty, A., Sgrò, C.M., Mirth, C.K. 2024. Untangling plastic responses to combined thermal and dietary stress in insects. Current Opinion in Insect Science. Doi:10.1016/j.cois.2024.101328

 

 

Transiently restricting individual amino acids protects Drosophila melanogaster against multiple stressors.

Fulton, T.L., Johnstone, J.N., Tan, J.J., Balagopal, K., Dedman, A., Chan, A.Y., Johnson, T.K., Mirth, C.K. and Piper, M.D.W. 2024. Transiently restricting individual amino acids protects Drosophila melanogaster against multiple stressors. Open Biology 14240093v Doi:10.1098/rsob.240093

 

 

Within population plastic responses to combined thermal-nutritional stress differ from those in response to single stressors, and are genetically independent across traits in both males and females.

Choy, Y.M.M., Walter, G.M., Mirth, C.K., Sgrò, C.M. 2024. Within population plastic responses to combined thermal-nutritional stress differ from those in response to single stressors, and are genetically independent across traits in both males and females. Journal of Evolutionary Biology, voae061. Doi:10.1093/jeb/voae061

 

 

Timing Drosophila development through steroid hormone action

Morrow, H., Mirth, C.K. 2024. Timing Drosophila development through steroid hormone action.Current Opinion in Genetics & Development 84. Doi:10.1016/j.gde.2023.102148

 

 

Temperature and nutrition do not interact to shape the evolution of metabolic rate. 

Alton, L.A., Kutz, T., Bywater, C.L., Lombardi, E., Cockerell, F.E., Layh, S., Winwood-Smith H., Arnold, P.A., Beaman, J.E., Walter, G.M., Monro, K., Mirth, C.K., Sgrò, C.M., White, C.R. 2024.Temperature and nutrition do not interact to shape the evolution of metabolic rate. Philosophical Transactions of the Royal Society B. Doi:10.1098/rstb.2022.0484

2023

Biosynthetic constraints on amino acid synthesis at the base of the food chain may determine their use in higher-order consumer genomes.

Gómez Ortega, J., Raubenheimer, D., Tyagi, S., Mirth, C.K., Piper, M.D.W. 2023. Biosynthetic constraints on amino acid synthesis at the base of the food chain may determine their use in higher-order consumer genomes. PLoS Genetics 19(2): e1010635. Doi:10.1371/journal.pgen.1010635

 

 

Drosophila melanogaster females prioritise dietary sterols for producing viable eggs.

Zanco, B., Rapley, L., Johnstone, J.N., Dedman, A., Mirth, C.K., Sgrò, C.M.,  Matthew D.W. Piper, M.D.W. 2023. Drosophila melanogaster females prioritise dietary sterols for producing viable eggs. Journal of Insect Physiology. Doi:10.1016/j.jinsphys.2022.104472

 

 

Within-population variation in body size plasticity in response to combined nutritional and thermal stress is partially independent from variation in development time.

Chakraborty, A., Walter, G.M., Monro, K., Alves, A.N., Mirth, C.K., & Sgrò, C.M. 2023. Within-population variation in body size plasticity in response to combined nutritional and thermal stress is partially independent from variation in development time. Journal of Evolutionary Biology, 00, 1– 16. Doi:10.1111/jeb.14099

 

 

Ageing impairs protein leveraging in a sex-specific manner in Drosophila melanogaster.

Rushby, H.J.,  Andrews, Z.B, Piper, M.D.W., Mirth, C.K. 2023. Ageing impairs protein leveraging in a sex-specific manner in Drosophila melanogaster. Animal Behaviour 195, 43-51. doi:10.1016/j.anbehav.2022.10.013

 

 

2022

Restricting a single amino acid cross-protects D. melanogaster from nicotine poisoning through mTORC1 and GCN2 signalling.

Fulton, T.L., Mirth, C.K., Piper, M.D.W. 2022. Restricting a single amino acid cross-protects D. melanogaster from nicotine poisoning through mTORC1 and GCN2 signalling. Open Biology 12. Doi:10.1098/rsob.220319

 

 

Rethinking the ecdysteroid source during Drosophila pupal–adult development.

Scanlan, J.L., Robin, C., Mirth, C.K. 2022. Rethinking the ecdysteroid source during Drosophila pupal–adult development. Insect Biochemistry and Molecular Biology, 103891. doi:10.1016/j.ibmb.2022.103891

 

 

Nutrigonometry I: using right-angle triangles to quantify nutritional trade-offs in performance landscapes. 

Morimoto, J., Conceição, P., Mirth, C., Lihoreau, M. 2022. Nutrigonometry I: using right-angle triangles to quantify nutritional trade-offs in performance landscapes. The American Naturalist. Doi:10.1086/723599

 

 

When does diet matter? The roles of larval and adult nutrition in regulating adult size traits.

Poças, G.M., Crosbie, A.E. & Mirth, C.K. 2022. When does diet matter? The roles of larval and adult nutrition in regulating adult size traits. Journal of Insect Physiology 139, 104051. Doi:10.1016/j.jinsphys.2020.104051

 

 

Amino acid quality modifies the quantitative availability of protein for reproduction in Drosophila melanogaster.

Ma, C., Mirth, C.K., Hall, M.D. & Piper, M.D.W. 2022. Amino acid quality modifies the quantitative availability of protein for reproduction in Drosophila melanogaster. Journal of Insect Physiology. Doi:10.1016/j.jinsphys.2020.104050

 

 

An integrative approach to dietary balance across the life course.

Raubenheimer, D., Senior, A.M., Mirth, C.K., Cui, Z., Hou, R., Le Couteur, D.G., Solon-Biet, S.M., Léopold, P., Simpson, S.J. 2022. An integrative approach to dietary balance across the life course. ISCIENCE doi:10.1016/j.isci.2022.104315

 

 

Genetic variation of macronutrient tolerance in Drosophila melanogaster.

Francis, D., Hasygar, K., Liu, Y., Alton, L.A., Johnstone, J., Needham, E.J., Pulpitel, T., Clark, T., Niranjan, H.N., Shang, V., Tong, V., Jiwnani, N., Audia, G., Alves, A.N., Sylow, L., Mirth, C., Neely, G.G., Yang, J., Hietakangas, V., Simpson S.J., Senior A.M. 2022. Genetic variation of macronutrient tolerance in Drosophila melanogaster. Nature Communications 13, 1637. Doi:10.1038/s41467-022-29183-x

 

 

Ecdysone coordinates plastic growth with robust pattern in the developing wing.

Alves, A.N., Oliveira, M.M.,  Koyama, T.,  Shingleton, A., Mirth, C.K. 2022. Ecdysone coordinates plastic growth with robust pattern in the developing wing. eLife 11, e72666. Doi:10.7554/eLife.72666

 

 

Target of Rapamycin Drives Unequal Responses to Essential Amino Acid Depletion for Egg Laying in Drosophila Melanogaster.

Alves, A.N., Sgrò, C.M., Piper, M.D.W., Mirth, C.K. 2022. Target of Rapamycin Drives Unequal Responses to Essential Amino Acid Depletion for Egg Laying in Drosophila Melanogaster. Frontiers in Cell and Developmental Biology 10:822685. Doi: 10.3389/fcell.2022.822685

 

 

Dietary restriction and lifespan: adaptive reallocation or somatic sacrifice?

Piper, M.D.W., Zanco, B., Sgrò, C.M., Adler, M.I., Mirth, C.K. and Bonduriansky, R. 2022. Dietary restriction and lifespan: adaptive reallocation or somatic sacrifice? FEBS Journal. Doi:10.1111/febs.16463

 

 

Maintaining robust size across environmental conditions through plastic brain growth dynamics.

Cobham, A.E.,  Neumann, B., Mirth, C.K. 2022.  Maintaining robust size across environmental conditions through plastic brain growth dynamics. Open Biology 12 (9), 220037. doi:10.1098/rsob.220037

 

 

Evaluating old truths: Final adult size in holometabolous insects is set by the end of larval development.

Hanna, L., Lamouret,  T., Poças, G.M., Mirth, C.K.,  Moczek, A.P., Nijhout, F.H., Abouheif, E. 2022. Evaluating old truths: Final adult size in holometabolous insects is set by the end of larval development. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution. Doi:10.1002/jez.b.23165

 

 

2021

The proximate sources of genetic variation in body size plasticity: the relative contributions of feeding behaviour and development in Drosophila melanogaster.

Chakraborty, A, Sgrò, C.M., Mirth, C.K. 2021. The proximate sources of genetic variation in body size plasticity: the relative contributions of feeding behaviour and development in Drosophila melanogaster. Journal of Insect Physiology. Doi:10.1016/j.jinsphys.2021.104321

 

 

The Number of Larval Molts Is Controlled by Hox in Caterpillars.

Daimon, T., Koyama, T., Yamamoto, G., Sezutsu, H., Mirth, C.K., Shinoda, T. 2021. The Number of Larval Molts Is Controlled by Hox in Caterpillars. Current Biology. Doi:10.1016/j.cub.2020.11.017